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Construction of Dimeric Drug-Loaded Polymeric Micelles with High Loading Efficiency for Cancer Therapy

Polymeric micelles (PMs) have been applied widely to transport hydrophobic drugs to tumor sites for cancer treatment. However, the low load efficiency of the drug in the PMs significantly reduces the therapeutic efficiency. We report here that disulfide-linked camptothecin (CPT) as a kind of dimeric...

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Detalles Bibliográficos
Autores principales: Yu, Bing, Meng, Qingye, Hu, Hao, Xu, Tao, Shen, Youqing, Cong, Hailin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6515377/
https://www.ncbi.nlm.nih.gov/pubmed/31013608
http://dx.doi.org/10.3390/ijms20081961