ChimeraMiner: An Improved Chimeric Read Detection Pipeline and Its Application in Single Cell Sequencing

As the most widely-used single cell whole genome amplification (WGA) approach, multiple displacement amplification (MDA) has a superior performance, due to the high-fidelity and processivity of phi29 DNA polymerase. However, chimeric reads, generated in MDA, cause severe disruption in many single-ce...

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Detalles Bibliográficos
Autores principales: Lu, Na, Li, Junji, Bi, Changwei, Guo, Jing, Tao, Yuhan, Luan, Kaihao, Tu, Jing, Lu, Zuhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6515389/
https://www.ncbi.nlm.nih.gov/pubmed/31010074
http://dx.doi.org/10.3390/ijms20081953

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6515389/
https://www.ncbi.nlm.nih.gov/pubmed/31010074
http://dx.doi.org/10.3390/ijms20081953

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