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Development of a mouse iron overload-induced liver injury model and evaluation of the beneficial effects of placenta extract on iron metabolism

Hepatic iron deposition is seen in cases of chronic hepatitis and cirrhosis, and is a hallmark of a poorer prognosis. Iron deposition is also found in non-alcoholic steatohepatitis (NASH) patients. We have now developed a mouse model of NASH with hepatic iron deposition by combining a methione- and...

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Detalles Bibliográficos
Autores principales: Yamauchi, Akihiro, Kamiyoshi, Akiko, Sakurai, Takayuki, Miyazaki, Hiroyuki, Hirano, Eiichi, Lim, Hong-Seok, Kaku, Taiichi, Shindo, Takayuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6515419/
https://www.ncbi.nlm.nih.gov/pubmed/31193082
http://dx.doi.org/10.1016/j.heliyon.2019.e01637