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Polymer coil–globule phase transition is a universal folding principle of Drosophila epigenetic domains

BACKGROUND: Localized functional domains within chromosomes, known as topologically associating domains (TADs), have been recently highlighted. In Drosophila, TADs are biochemically defined by epigenetic marks, this suggesting that the 3D arrangement may be the “missing link” between epigenetics and...

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Detalles Bibliográficos
Autores principales: Lesage, Antony, Dahirel, Vincent, Victor, Jean-Marc, Barbi, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6515630/
https://www.ncbi.nlm.nih.gov/pubmed/31084607
http://dx.doi.org/10.1186/s13072-019-0269-6