Cargando…

Induction of tolerogenic dendritic cells by activated TGF-β/Akt/Smad2 signaling in RIG-I-deficient stemness-high human liver cancer cells

BACKGROUND: Dendritic cells (DCs) alter their role from being immunostimulatory to immunosuppressive at advanced stages of tumor progression, but the influence of cancer stem cells (CSCs) and their secreted factors on generation and phenotypic change of DCs is unknown. Retinoic acid-inducible gene I...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhong, Ming, Zhong, Cheng, Cui, Wen, Wang, Guanghui, Zheng, Gongpu, Li, Li, Zhang, Jing, Ren, Rujing, Gao, Huijei, Wang, Tingting, Li, Xin, Che, Jiantu, Gohda, Eiichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6515680/
https://www.ncbi.nlm.nih.gov/pubmed/31088527
http://dx.doi.org/10.1186/s12885-019-5670-9