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Novel predictive epigenetic signature for temozolomide in non-G-CIMP glioblastomas

OBJECTIVE: To identify novel epigenetic signatures that could provide predictive information that is complementary to promoter methylation status of the O-6-methylguanine-DNA methyltransferase (MGMT) gene for predicting temozolomide (TMZ) response, among glioblastomas (GBMs) without glioma-CpGs isla...

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Detalles Bibliográficos
Autores principales: Yin, An-An, He, Ya-Long, Etcheverry, Amandine, Liu, Yu-He, Aubry, Marc, Barnholtz-Sloan, Jill, Liu, Bo-Lin, Mosser, Jean, Lu, Zi-Fan, Zhang, Xiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6515684/
https://www.ncbi.nlm.nih.gov/pubmed/31088577
http://dx.doi.org/10.1186/s13148-019-0670-9