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Novel predictive epigenetic signature for temozolomide in non-G-CIMP glioblastomas
OBJECTIVE: To identify novel epigenetic signatures that could provide predictive information that is complementary to promoter methylation status of the O-6-methylguanine-DNA methyltransferase (MGMT) gene for predicting temozolomide (TMZ) response, among glioblastomas (GBMs) without glioma-CpGs isla...
Autores principales: | Yin, An-An, He, Ya-Long, Etcheverry, Amandine, Liu, Yu-He, Aubry, Marc, Barnholtz-Sloan, Jill, Liu, Bo-Lin, Mosser, Jean, Lu, Zi-Fan, Zhang, Xiang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6515684/ https://www.ncbi.nlm.nih.gov/pubmed/31088577 http://dx.doi.org/10.1186/s13148-019-0670-9 |
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