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Hypoxic preconditioning improves long‐term functional outcomes after neonatal hypoxia–ischemic injury by restoring white matter integrity and brain development

AIMS: Neonatal hypoxia–ischemia (H/I) results in gray and white matter injury, characterized by neuronal loss, failure of neural network formation, retarded myelin formation, and abnormal accumulation of oligodendrocyte progenitor cells (OPCs). These changes lead to severe neurological deficits and...

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Detalles Bibliográficos
Autores principales: Xu, Ming‐Yue, Wang, Yang‐Fan, Wei, Peng‐Ju, Gao, Yan‐Qin, Zhang, Wen‐Ting
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6515700/
https://www.ncbi.nlm.nih.gov/pubmed/30689302
http://dx.doi.org/10.1111/cns.13102