Modeling vanishing white matter disease with patient‐derived induced pluripotent stem cells reveals astrocytic dysfunction

AIMS: Vanishing white matter disease (VWM) is an inherited leukoencephalopathy in children attributed to mutations in EIF2B1–5, encoding five subunits of eukaryotic translation initiation factor 2B (eIF2B). Although the defects are in the housekeeping genes, glial cells are selectively involved in V...

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Detalles Bibliográficos
Autores principales: Zhou, Ling, Li, Peng, Chen, Na, Dai, Li‐Fang, Gao, Kai, Liu, Yi‐Nan, Shen, Li, Wang, Jing‐Min, Jiang, Yu‐Wu, Wu, Ye
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6515702/
https://www.ncbi.nlm.nih.gov/pubmed/30720246
http://dx.doi.org/10.1111/cns.13107

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6515702/
https://www.ncbi.nlm.nih.gov/pubmed/30720246
http://dx.doi.org/10.1111/cns.13107

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