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GPR30‐mediated estrogenic regulation of actin polymerization and spatial memory involves SRC‐1 and PI3K‐mTORC2 in the hippocampus of female mice

AIMS: The G‐protein‐coupled estrogen receptor GPR30 (also referred to as GPER) has been implicated in the estrogenic regulation of hippocampal plasticity and spatial memory; however, the molecular mechanisms are largely unclear. METHODS: In this study, we initially examined the levels of GPR30 in th...

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Detalles Bibliográficos
Autores principales: Zhang, Yuan‐Yuan, Liu, Meng‐Ying, Liu, Zhi, Zhao, Ji‐Kai, Zhao, Yan‐Gang, He, Li, Li, Wei, Zhang, Ji‐Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6515707/
https://www.ncbi.nlm.nih.gov/pubmed/30714337
http://dx.doi.org/10.1111/cns.13108