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The IgA Isotype of Anti-β2 Glycoprotein I Antibodies Recognizes Epitopes in Domains 3, 4, and 5 That Are Located in a Lateral Zone of the Molecule (L-Shaped)

Background: Antiphospholipid syndrome (APS) is characterized by thrombosis and/or pregnancy morbidity with presence of anti-phospholipid antibodies (aPL). The APS classification criteria only consider the aPL of IgG/IgM isotype, however testing of aPL of IgA isotype is recommended when APS is suspec...

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Detalles Bibliográficos
Autores principales: Serrano, Manuel, Martinez-Flores, Jose Angel, Norman, Gary L., Naranjo, Laura, Morales, Jose Maria, Serrano, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6515947/
https://www.ncbi.nlm.nih.gov/pubmed/31134087
http://dx.doi.org/10.3389/fimmu.2019.01031