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The IgA Isotype of Anti-β2 Glycoprotein I Antibodies Recognizes Epitopes in Domains 3, 4, and 5 That Are Located in a Lateral Zone of the Molecule (L-Shaped)
Background: Antiphospholipid syndrome (APS) is characterized by thrombosis and/or pregnancy morbidity with presence of anti-phospholipid antibodies (aPL). The APS classification criteria only consider the aPL of IgG/IgM isotype, however testing of aPL of IgA isotype is recommended when APS is suspec...
Autores principales: | Serrano, Manuel, Martinez-Flores, Jose Angel, Norman, Gary L., Naranjo, Laura, Morales, Jose Maria, Serrano, Antonio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6515947/ https://www.ncbi.nlm.nih.gov/pubmed/31134087 http://dx.doi.org/10.3389/fimmu.2019.01031 |
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