The angiotensin‐(1‐7)/Mas receptor axis protects from endothelial cell senescence via klotho and Nrf2 activation

Endothelial cell senescence is a hallmark of vascular aging that predisposes to vascular disease. We aimed to explore the capacity of the renin–angiotensin system (RAS) heptapeptide angiotensin (Ang)‐(1‐7) to counteract human endothelial cell senescence and to identify intracellular pathways mediati...

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Detalles Bibliográficos
Autores principales: Romero, Alejandra, San Hipólito‐Luengo, Álvaro, Villalobos, Laura A., Vallejo, Susana, Valencia, Inés, Michalska, Patrycja, Pajuelo‐Lozano, Natalia, Sánchez‐Pérez, Isabel, León, Rafael, Bartha, José Luis, Sanz, María Jesús, Erusalimsky, Jorge D., Sánchez‐Ferrer, Carlos F., Romacho, Tania, Peiró, Concepción
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Original Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6516147/
https://www.ncbi.nlm.nih.gov/pubmed/30773786
http://dx.doi.org/10.1111/acel.12913

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6516147/
https://www.ncbi.nlm.nih.gov/pubmed/30773786
http://dx.doi.org/10.1111/acel.12913

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