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Caloric restriction controls stationary phase survival through Protein Kinase A (PKA) and cytosolic pH

Calorie restriction is the only physiological intervention that extends lifespan throughout all kingdoms of life. In the budding yeast Saccharomyces cerevisiae, cytosolic pH (pH(c)) controls growth and responds to nutrient availability, decreasing upon glucose depletion. We investigated the interact...

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Detalles Bibliográficos
Autores principales: Dolz‐Edo, Laura, van der Deen, Margaretha, Brul, Stanley, Smits, Gertien Jacoba
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6516148/
https://www.ncbi.nlm.nih.gov/pubmed/30790427
http://dx.doi.org/10.1111/acel.12921