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Accelerated bio‐cognitive aging in Down syndrome: State of the art and possible deceleration strategies

Down syndrome (DS) has been proposed by George Martin as a segmental progeroid syndrome since 1978. In fact, DS persons suffer from several age‐associated disorders much earlier than euploid persons. Furthermore, a series of recent studies have found that DS persons display elevated levels of age bi...

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Detalles Bibliográficos
Autores principales: Franceschi, Claudio, Garagnani, Paolo, Gensous, Noémie, Bacalini, Maria Giulia, Conte, Maria, Salvioli, Stefano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6516152/
https://www.ncbi.nlm.nih.gov/pubmed/30768754
http://dx.doi.org/10.1111/acel.12903