Aged‐senescent cells contribute to impaired heart regeneration

Aging leads to increased cellular senescence and is associated with decreased potency of tissue‐specific stem/progenitor cells. Here, we have done an extensive analysis of cardiac progenitor cells (CPCs) isolated from human subjects with cardiovascular disease, aged 32–86 years. In aged subjects (&g...

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Detalles Bibliográficos
Autores principales: Lewis‐McDougall, Fiona C., Ruchaya, Prashant J., Domenjo‐Vila, Eva, Shin Teoh, Tze, Prata, Larissa, Cottle, Beverley J., Clark, James E., Punjabi, Prakash P., Awad, Wael, Torella, Daniele, Tchkonia, Tamara, Kirkland, James L., Ellison‐Hughes, Georgina M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Original Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6516154/
https://www.ncbi.nlm.nih.gov/pubmed/30854802
http://dx.doi.org/10.1111/acel.12931

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6516154/
https://www.ncbi.nlm.nih.gov/pubmed/30854802
http://dx.doi.org/10.1111/acel.12931

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