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Aged‐senescent cells contribute to impaired heart regeneration
Aging leads to increased cellular senescence and is associated with decreased potency of tissue‐specific stem/progenitor cells. Here, we have done an extensive analysis of cardiac progenitor cells (CPCs) isolated from human subjects with cardiovascular disease, aged 32–86 years. In aged subjects (&g...
Autores principales: | Lewis‐McDougall, Fiona C., Ruchaya, Prashant J., Domenjo‐Vila, Eva, Shin Teoh, Tze, Prata, Larissa, Cottle, Beverley J., Clark, James E., Punjabi, Prakash P., Awad, Wael, Torella, Daniele, Tchkonia, Tamara, Kirkland, James L., Ellison‐Hughes, Georgina M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6516154/ https://www.ncbi.nlm.nih.gov/pubmed/30854802 http://dx.doi.org/10.1111/acel.12931 |
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