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Cardiolipin remodeling by ALCAT1 links mitochondrial dysfunction to Parkinson’s diseases

Cardiolipin (CL) is a mitochondrial signature phospholipid that is required for membrane structure, respiration, dynamics, and mitophagy. Oxidative damage of CL by reactive oxygen species is implicated in the pathogenesis of Parkinson's disease (PD), but the underlying cause remains elusive. Th...

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Detalles Bibliográficos
Autores principales: Song, Chengjie, Zhang, Jun, Qi, Shasha, Liu, Zhen, Zhang, Xiaoyang, Zheng, Yue, Andersen, John‐Paul, Zhang, Weiping, Strong, Randy, Martinez, Paul Anthony, Musi, Nicolas, Nie, Jia, Shi, Yuguang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6516155/
https://www.ncbi.nlm.nih.gov/pubmed/30838774
http://dx.doi.org/10.1111/acel.12941