Cargando…

Cardiolipin remodeling by ALCAT1 links mitochondrial dysfunction to Parkinson’s diseases

Cardiolipin (CL) is a mitochondrial signature phospholipid that is required for membrane structure, respiration, dynamics, and mitophagy. Oxidative damage of CL by reactive oxygen species is implicated in the pathogenesis of Parkinson's disease (PD), but the underlying cause remains elusive. Th...

Descripción completa

Detalles Bibliográficos
Autores principales:	Song, Chengjie, Zhang, Jun, Qi, Shasha, Liu, Zhen, Zhang, Xiaoyang, Zheng, Yue, Andersen, John‐Paul, Zhang, Weiping, Strong, Randy, Martinez, Paul Anthony, Musi, Nicolas, Nie, Jia, Shi, Yuguang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2019
Materias:	Original Papers
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6516155/ https://www.ncbi.nlm.nih.gov/pubmed/30838774 http://dx.doi.org/10.1111/acel.12941

Ejemplares similares

Pharmacological inhibition of ALCAT1 mitigates amyotrophic lateral sclerosis by attenuating SOD1 protein aggregation
por: Liu, Xueling, et al.
Publicado: (2022)

Emerging roles of cardiolipin remodeling in mitochondrial dysfunction associated with diabetes, obesity, and cardiovascular diseases
por: Shi, Yuguang
Publicado: (2010)

Defective Phosphatidylglycerol Remodeling Causes Hepatopathy, Linking Mitochondrial Dysfunction to Hepatosteatosis
por: Zhang, Xiaoyang, et al.
Publicado: (2019)

Human Trifunctional Protein Alpha Links Cardiolipin Remodeling to Beta-Oxidation
por: Taylor, William A., et al.
Publicado: (2012)

ALCAT1 Overexpression Affects Supercomplex Formation and Increases ROS in Respiring Mitochondria
por: Rieger, Bettina, et al.
Publicado: (2019)

Altered cardiolipin metabolism is associated with cardiac mitochondrial dysfunction in pulmonary vascular remodeled perinatal rat pups
por: Cole, Laura K., et al.
Publicado: (2022)

Insights into complex I assembly: Function of NDUFAF1 and a link with cardiolipin remodeling
por: Schiller, Jonathan, et al.
Publicado: (2022)

Control and Data Acquisition System for Lower Hybrid Current Drive in Alcator C-Mod
por: Basse, N P, et al.
Publicado: (2003)

Deacylation on the matrix side of the mitochondrial inner membrane regulates cardiolipin remodeling
por: Baile, Matthew G., et al.
Publicado: (2013)

Spatiotemporal AMPKα2 deletion in mice induces cardiac dysfunction, fibrosis and cardiolipin remodeling associated with mitochondrial dysfunction in males only
por: Grimbert, Lucile, et al.
Publicado: (2021)

Construction, Calibration and Testing of a Multi-Waveguide Array for the Application of LHCD on Alcator C-MOD
por: Wilson, J R, et al.
Publicado: (2003)

Optimized AT Target Plasma Studies in Alcator C-Mod with I$_{p}$-Ramp and Intense ICRH
por: Porkolab, M, et al.
Publicado: (2003)

The Roles of FGF21 and ALCAT1 in Aerobic Exercise-Induced Cardioprotection of Postmyocardial Infarction Mice
por: Bo, Wenyan, et al.
Publicado: (2021)

Cardiolipin, Perhydroxyl Radicals, and Lipid Peroxidation in Mitochondrial Dysfunctions and Aging
por: Panov, Alexander V., et al.
Publicado: (2020)

Defective Mitochondrial Cardiolipin Remodeling Dampens HIF-1α Expression in Hypoxia
por: Chowdhury, Arpita, et al.
Publicado: (2018)

Double bonds of unsaturated fatty acids differentially regulate mitochondrial cardiolipin remodeling
por: Ting, Hsiu-Chi, et al.
Publicado: (2019)

Increased mitochondrial protein import and cardiolipin remodelling upon early mtUPR
por: Poveda-Huertes, Daniel, et al.
Publicado: (2021)

Selective remodeling of cardiolipin fatty acids in the aged rat heart
por: Lee, Ho-Joo, et al.
Publicado: (2006)

Sex-specific cardiac cardiolipin remodelling after doxorubicin treatment
por: Moulin, Maryline, et al.
Publicado: (2015)

Metabolic Alterations Caused by Defective Cardiolipin Remodeling in Inherited Cardiomyopathies
por: Wasmus, Christina, et al.
Publicado: (2020)

Diet Restriction Impact on High-Fat-Diet-Induced Obesity by Regulating Mitochondrial Cardiolipin Biosynthesis and Remodeling
por: Li, Qiaoyu, et al.
Publicado: (2023)

The Role of Cardiolipin and Mitochondrial Damage in Kidney Transplant
por: Miranda-Díaz, Alejandra Guillermina, et al.
Publicado: (2019)

Safety and Efficacy of Acetyl-DL-Leucine in Certain Types of Cerebellar Ataxia: The ALCAT Randomized Clinical Crossover Trial
por: Feil, Katharina, et al.
Publicado: (2021)

Cardioprotection Attributed to Aerobic Exercise-Mediated Inhibition of ALCAT1 and Oxidative Stress-Induced Apoptosis in MI Rats
por: Liu, Niu, et al.
Publicado: (2022)

Impact of Antioxidants on Cardiolipin Oxidation in Liposomes: Why Mitochondrial Cardiolipin Serves as an Apoptotic Signal?
por: Lokhmatikov, Alexey V., et al.
Publicado: (2016)

A Mathematical Model for the Determination of Steady-State Cardiolipin Remodeling Mechanisms Using Lipidomic Data
por: Zhang, Lu, et al.
Publicado: (2011)

Neurodegeneration and Motor Dysfunction in Mice Lacking Cytosolic and Mitochondrial Aldehyde Dehydrogenases: Implications for Parkinson's Disease
por: Wey, Margaret Chia-Ying, et al.
Publicado: (2012)

Cell Cycle Arrest and Cell Survival Induce Reverse Trends of Cardiolipin Remodeling
por: Chao, Yu-Jen, et al.
Publicado: (2014)

Barth syndrome: A life-threatening disorder caused by abnormal cardiolipin remodeling
por: Raja, Vaishnavi, et al.
Publicado: (2017)

New C-Terminal Conserved Regions of Tafazzin, a Catalyst of Cardiolipin Remodeling
por: Shilovsky, Gregory A., et al.
Publicado: (2019)

Current Knowledge on the Role of Cardiolipin Remodeling in the Context of Lipid Oxidation and Barth Syndrome
por: Liang, Zhuqing, et al.
Publicado: (2022)

Unveiling the last missing link of the cardiolipin synthetic pathway in mitochondria
por: Tamura, Yasushi, et al.
Publicado: (2013)

Molecular structural diversity of mitochondrial cardiolipins
por: Oemer, Gregor, et al.
Publicado: (2018)

Role of Cardiolipin in Mitochondrial Signaling Pathways
por: Dudek, Jan
Publicado: (2017)

Interaction of Alpha-Synuclein With Lipids: Mitochondrial Cardiolipin as a Critical Player in the Pathogenesis of Parkinson’s Disease
por: Gilmozzi, Valentina, et al.
Publicado: (2020)

Neurochemical and motor changes in mice with combined mutations linked to Parkinson’s disease
por: Bai, Xiang, et al.
Publicado: (2017)

Lifespan Extension of Podospora anserina Mic60-Subcomplex Mutants Depends on Cardiolipin Remodeling
por: Marschall, Lisa-Marie, et al.
Publicado: (2022)

2176. Cardiolipin Synthases Play Redundant Roles And Are Required for Membrane Remodeling in Daptomycin Resistant Enterococcus faecalis
por: Nguyen, April, et al.
Publicado: (2023)

Cardiolipin Regulates the Activity of the Mitochondrial ABC Transporter ABCB10
por: Zhang, Tianqi, et al.
Publicado: (2023)

Cardiolipin, the Mitochondrial Signature Lipid: Implication in Cancer
por: Ahmadpour, Seyedeh Tayebeh, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_v8ul24lmqr9ig3ggbagihka2jd