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DAF‐16 stabilizes the aging transcriptome and is activated in mid‐aged Caenorhabditis elegans to cope with internal stress

The roles and regulatory mechanisms of transcriptome changes during aging are unclear. It has been proposed that the transcriptome suffers decay during aging owing to age‐associated down‐regulation of transcription factors. In this study, we characterized the role of a transcription factor DAF‐16, w...

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Detalles Bibliográficos
Autores principales: Li, Shang‐Tong, Zhao, Han‐Qing, Zhang, Pan, Liang, Chung‐Yi, Zhang, Yan‐Ping, Hsu, Ao‐Lin, Dong, Meng‐Qiu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6516157/
https://www.ncbi.nlm.nih.gov/pubmed/30773782
http://dx.doi.org/10.1111/acel.12896