NMNAT2‐mediated NAD(+) generation is essential for quality control of aged oocytes

Advanced maternal age has been reported to impair oocyte quality; however, the underlying mechanisms remain to be explored. In the present study, we identified the lowered NAD(+) content and decreased expression of NMNAT2 protein in oocytes from old mice. Specific depletion of NMNAT2 in mouse oocyte...

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Detalles Bibliográficos
Autores principales: Wu, Xinghan, Hu, Feifei, Zeng, Juan, Han, Longsen, Qiu, Danhong, Wang, Haichao, Ge, Juan, Ying, Xiaoyan, Wang, Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Original Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6516161/
https://www.ncbi.nlm.nih.gov/pubmed/30909324
http://dx.doi.org/10.1111/acel.12955

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6516161/
https://www.ncbi.nlm.nih.gov/pubmed/30909324
http://dx.doi.org/10.1111/acel.12955

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