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The leptin sensitizer celastrol reduces age‐associated obesity and modulates behavioral rhythms
The prevalence of obesity increases with age in humans and in rodents. Age‐related obesity is characterized by leptin resistance and associated with heightened risk of metabolic disorders. However, the effect of leptin resistance per se has been difficult to disentangle from other effects of aging....
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6516176/ https://www.ncbi.nlm.nih.gov/pubmed/30821426 http://dx.doi.org/10.1111/acel.12874 |