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Glycine supplementation extends lifespan of male and female mice

Diets low in methionine extend lifespan of rodents, though through unknown mechanisms. Glycine can mitigate methionine toxicity, and a small prior study has suggested that supplemental glycine could extend lifespan of Fischer 344 rats. We therefore evaluated the effects of an 8% glycine diet on life...

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Detalles Bibliográficos
Autores principales: Miller, Richard A., Harrison, David E., Astle, C. Michael, Bogue, Molly A., Brind, Joel, Fernandez, Elizabeth, Flurkey, Kevin, Javors, Martin, Ladiges, Warren, Leeuwenburgh, Christiaan, Macchiarini, Francesca, Nelson, James, Ryazanov, Alexey G., Snyder, Jessica, Stearns, Timothy M., Vaughan, Douglas E., Strong, Randy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6516426/
https://www.ncbi.nlm.nih.gov/pubmed/30916479
http://dx.doi.org/10.1111/acel.12953