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Endothelial toll‐like receptor 4 maintains lung integrity via epigenetic suppression of p16(INK4a)
We previously reported that the canonical innate immune receptor toll‐like receptor 4 (TLR4) is critical in maintaining lung integrity. However, the molecular mechanisms via which TLR4 mediates its effect remained unclear. In the present study, we identified distinct contributions of lung endothelia...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6516428/ https://www.ncbi.nlm.nih.gov/pubmed/30790400 http://dx.doi.org/10.1111/acel.12914 |