JNK modifies neuronal metabolism to promote proteostasis and longevity

Aging is associated with a progressive loss of tissue and metabolic homeostasis. This loss can be delayed by single‐gene perturbations, increasing lifespan. How such perturbations affect metabolic and proteostatic networks to extend lifespan remains unclear. Here, we address this question by compreh...

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Detalles Bibliográficos
Autores principales: Wang, Lifen, Davis, Sonnet S., Borch Jensen, Martin, Rodriguez‐Fernandez, Imilce A., Apaydin, Cagsar, Juhasz, Gabor, Gibson, Bradford W., Schilling, Birgit, Ramanathan, Arvind, Ghaemmaghami, Sina, Jasper, Heinrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Original Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6516429/
https://www.ncbi.nlm.nih.gov/pubmed/30810280
http://dx.doi.org/10.1111/acel.12849

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6516429/
https://www.ncbi.nlm.nih.gov/pubmed/30810280
http://dx.doi.org/10.1111/acel.12849

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