Oxidized LDL, homocysteine, homocysteine thiolactone and advanced glycation end products act as pro-oxidant metabolites inducing cytokine release, macrophage infiltration and pro-angiogenic effect in ARPE-19 cells

Age-related Macular Degeneration (AMD) is one of the major vision-threatening diseases of the eye. Oxidative stress is one of the key factors in the onset and progression of AMD. In this study, metabolites associated with AMD pathology more so at the systemic level namely, oxidized LDL (oxLDL), homo...

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Detalles Bibliográficos
Autores principales: AnandBabu, Kannadasan, Sen, Parveen, Angayarkanni, Narayanasamy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6516731/
https://www.ncbi.nlm.nih.gov/pubmed/31086404
http://dx.doi.org/10.1371/journal.pone.0216899

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6516731/
https://www.ncbi.nlm.nih.gov/pubmed/31086404
http://dx.doi.org/10.1371/journal.pone.0216899

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