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A 3D culture model of innervated human skeletal muscle enables studies of the adult neuromuscular junction

Two-dimensional (2D) human skeletal muscle fiber cultures are ill-equipped to support the contractile properties of maturing muscle fibers. This limits their application to the study of adult human neuromuscular junction (NMJ) development, a process requiring maturation of muscle fibers in the prese...

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Detalles Bibliográficos
Autores principales: Afshar Bakooshli, Mohsen, Lippmann, Ethan S, Mulcahy, Ben, Iyer, Nisha, Nguyen, Christine T, Tung, Kayee, Stewart, Bryan A, van den Dorpel, Hubrecht, Fuehrmann, Tobias, Shoichet, Molly, Bigot, Anne, Pegoraro, Elena, Ahn, Henry, Ginsberg, Howard, Zhen, Mei, Ashton, Randolph Scott, Gilbert, Penney M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6516829/
https://www.ncbi.nlm.nih.gov/pubmed/31084710
http://dx.doi.org/10.7554/eLife.44530