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A multiplexed DNA FISH strategy for assessing genome architecture in Caenorhabditis elegans

Eukaryotic DNA is highly organized within nuclei and this organization is important for genome function. Fluorescent in situ hybridization (FISH) approaches allow 3D architectures of genomes to be visualized. Scalable FISH technologies, which can be applied to whole animals, are needed to help unrav...

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Detalles Bibliográficos
Autores principales: Fields, Brandon D, Nguyen, Son C, Nir, Guy, Kennedy, Scott
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6516958/
https://www.ncbi.nlm.nih.gov/pubmed/31084706
http://dx.doi.org/10.7554/eLife.42823