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Differential microglia and macrophage profiles in human IDH-mutant and -wild type glioblastoma

Microglia and macrophages are the largest component of the inflammatory infiltrate in glioblastoma (GBM). However, whether there are differences in their representation and activity in the prognostically-favorable isocitrate dehydrogenase (IDH)-mutated compared to -wild type GBMs is unknown. Studies...

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Detalles Bibliográficos
Autores principales: Poon, Candice C., Gordon, Paul M.K., Liu, Katherine, Yang, Runze, Sarkar, Susobhan, Mirzaei, Reza, Ahmad, Shiekh Tanveer, Hughes, Martha L., Yong, V. Wee, Kelly, John J.P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6517100/
https://www.ncbi.nlm.nih.gov/pubmed/31139325
http://dx.doi.org/10.18632/oncotarget.26863