Dysregulation of the TOX-RUNX3 pathway in cutaneous T-cell lymphoma

Studies have examined gene expression changes in Sézary syndrome (SS), but disease pathogenesis remains largely unknown, and diagnosis and treatment are difficult. TOX is a transcription factor involved in CD4+ T-cell development with downstream effects on RUNX3, a known tumor suppressor gene. We so...

Descripción completa

Detalles Bibliográficos
Autores principales: Dulmage, Brittany O., Akilov, Oleg, Vu, John R., Falo, Louis D., Geskin, Larisa J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6517103/
https://www.ncbi.nlm.nih.gov/pubmed/31139323
http://dx.doi.org/10.18632/oncotarget.5742

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6517103/
https://www.ncbi.nlm.nih.gov/pubmed/31139323
http://dx.doi.org/10.18632/oncotarget.5742

Ejemplares similares