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Dysregulation of the TOX-RUNX3 pathway in cutaneous T-cell lymphoma
Studies have examined gene expression changes in Sézary syndrome (SS), but disease pathogenesis remains largely unknown, and diagnosis and treatment are difficult. TOX is a transcription factor involved in CD4+ T-cell development with downstream effects on RUNX3, a known tumor suppressor gene. We so...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Impact Journals LLC
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6517103/ https://www.ncbi.nlm.nih.gov/pubmed/31139323 http://dx.doi.org/10.18632/oncotarget.5742 |