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Selection of a novel DNA aptamer against OFA/iLRP for targeted delivery of doxorubicin to AML cells

The standard treatment for most acute myeloid leukemia (AML) is chemotherapy, which is often associated with severe adverse effects. One strategy to reduce the adverse effects is targeted therapy that can selectively deliver anticancer drugs to tumor cells. Immature laminin receptor protein (OFA/iLR...

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Detalles Bibliográficos
Autores principales: An, Yacong, Hu, Yan, Li, Xundou, Li, Zhaoyi, Duan, Jinhong, Yang, Xian-Da
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6517398/
https://www.ncbi.nlm.nih.gov/pubmed/31089250
http://dx.doi.org/10.1038/s41598-019-43910-3