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Selection of a novel DNA aptamer against OFA/iLRP for targeted delivery of doxorubicin to AML cells
The standard treatment for most acute myeloid leukemia (AML) is chemotherapy, which is often associated with severe adverse effects. One strategy to reduce the adverse effects is targeted therapy that can selectively deliver anticancer drugs to tumor cells. Immature laminin receptor protein (OFA/iLR...
Autores principales: | An, Yacong, Hu, Yan, Li, Xundou, Li, Zhaoyi, Duan, Jinhong, Yang, Xian-Da |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6517398/ https://www.ncbi.nlm.nih.gov/pubmed/31089250 http://dx.doi.org/10.1038/s41598-019-43910-3 |
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