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COPII proteins exhibit distinct subdomains within each ER exit site for executing their functions

Secretory proteins are exported from special domains of the endoplasmic reticulum (ER) termed ER exit sites, via COPII-coated carriers. We recently showed that TANGO1 and Sec16 cooperatively organize mammalian ER exit sites for efficient secretion. However, the detailed spatial organization of mamma...

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Detalles Bibliográficos
Autores principales: Maeda, Miharu, Kurokawa, Kazuo, Katada, Toshiaki, Nakano, Akihiko, Saito, Kota
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6517409/
https://www.ncbi.nlm.nih.gov/pubmed/31089171
http://dx.doi.org/10.1038/s41598-019-43813-3