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COPII proteins exhibit distinct subdomains within each ER exit site for executing their functions
Secretory proteins are exported from special domains of the endoplasmic reticulum (ER) termed ER exit sites, via COPII-coated carriers. We recently showed that TANGO1 and Sec16 cooperatively organize mammalian ER exit sites for efficient secretion. However, the detailed spatial organization of mamma...
Autores principales: | Maeda, Miharu, Kurokawa, Kazuo, Katada, Toshiaki, Nakano, Akihiko, Saito, Kota |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6517409/ https://www.ncbi.nlm.nih.gov/pubmed/31089171 http://dx.doi.org/10.1038/s41598-019-43813-3 |
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