The mechanism of DNA unwinding by the eukaryotic replicative helicase

Accurate DNA replication is tightly regulated in eukaryotes to ensure genome stability during cell division and is performed by the multi-protein replisome. At the core an AAA+ hetero-hexameric complex, Mcm2-7, together with GINS and Cdc45 form the active replicative helicase Cdc45/Mcm2-7/GINS (CMG)...

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Detalles Bibliográficos
Autores principales: Burnham, Daniel R., Kose, Hazal B., Hoyle, Rebecca B., Yardimci, Hasan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6517413/
https://www.ncbi.nlm.nih.gov/pubmed/31089141
http://dx.doi.org/10.1038/s41467-019-09896-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6517413/
https://www.ncbi.nlm.nih.gov/pubmed/31089141
http://dx.doi.org/10.1038/s41467-019-09896-2

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