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mGluR1 in cerebellar Purkinje cells is essential for the formation but not expression of associative eyeblink memory

Classical eyeblink conditioning is a representative associative motor learning that requires both the cerebellar cortex and the deep cerebellar nucleus (DCN). Metabotropic glutamate receptor subtype 1 (mGluR1) is richly expressed in Purkinje cells (PCs) of the cerebellar cortex. Global mGluR1 knock-...

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Detalles Bibliográficos
Autores principales: Nakao, Harumi, Kishimoto, Yasushi, Hashimoto, Kouichi, Kitamura, Kazuo, Yamasaki, Miwako, Nakao, Kazuki, Watanabe, Masahiko, Kano, Masanobu, Kirino, Yutaka, Aiba, Atsu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6517439/
https://www.ncbi.nlm.nih.gov/pubmed/31089195
http://dx.doi.org/10.1038/s41598-019-43744-z