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IL-1β, IL-23, and TGF-β drive plasticity of human ILC2s towards IL-17-producing ILCs in nasal inflammation

Innate lymphoid cells (ILCs) are crucial for the immune surveillance at mucosal sites. ILCs coordinate early eradication of pathogens and contribute to tissue healing and remodeling, features that are dysfunctional in patients with cystic fibrosis (CF). The mechanisms by which ILCs contribute to CF-...

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Detalles Bibliográficos
Autores principales: Golebski, Korneliusz, Ros, Xavier R., Nagasawa, Maho, van Tol, Sophie, Heesters, Balthasar A., Aglmous, Hajar, Kradolfer, Chantal M. A., Shikhagaie, Medya M., Seys, Sven, Hellings, P. W., van Drunen, Cornelis M., Fokkens, Wytske J., Spits, Hergen, Bal, Suzanne M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6517442/
https://www.ncbi.nlm.nih.gov/pubmed/31089134
http://dx.doi.org/10.1038/s41467-019-09883-7