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Identification of the iduronate-2-sulfatase proteome in wild-type mouse brain

Iduronate-2-sulfatase (IDS) is a lysosomal enzyme involved in the metabolism of the glycosaminoglycans heparan (HS) and dermatan (DS) sulfate. Mutations on IDS gene produce mucopolysaccharidosis II (MPS II), characterized by the lysosomal accumulation of HS and DS, leading to severe damage of the ce...

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Detalles Bibliográficos
Autores principales: Cardona, Carolina, Benincore, Eliana, Pimentel, Natalia, Reyes, Luis H., Patarroyo, Camilo, Rodríguez-López, Alexander, Martin-Rufian, M., Barrera, Luis Alejandro, Alméciga-Díaz, Carlos J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6517578/
https://www.ncbi.nlm.nih.gov/pubmed/31193135
http://dx.doi.org/10.1016/j.heliyon.2019.e01667