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Activation of Th lymphocytes alters pattern expression and cellular location of VIP receptors in healthy donors and early arthritis patients

Vasoactive Intestinal Peptide (VIP) is an important immunomodulator of CD4(+) cells in normal and pathological conditions, which exerts its anti-inflammatory and immunomodulatory actions through VPAC receptors, VPAC(1) and VPAC(2). Only a decrease in the expression of VPAC(1) mRNA on Th cells upon a...

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Detalles Bibliográficos
Autores principales: Villanueva-Romero, R., Gutiérrez-Cañas, I., Carrión, M., González-Álvaro, I., Rodríguez-Frade, J. M., Mellado, M., Martínez, C., Gomariz, R. P., Juarranz, Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6517580/
https://www.ncbi.nlm.nih.gov/pubmed/31089161
http://dx.doi.org/10.1038/s41598-019-43717-2