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Activation of Th lymphocytes alters pattern expression and cellular location of VIP receptors in healthy donors and early arthritis patients
Vasoactive Intestinal Peptide (VIP) is an important immunomodulator of CD4(+) cells in normal and pathological conditions, which exerts its anti-inflammatory and immunomodulatory actions through VPAC receptors, VPAC(1) and VPAC(2). Only a decrease in the expression of VPAC(1) mRNA on Th cells upon a...
Autores principales: | Villanueva-Romero, R., Gutiérrez-Cañas, I., Carrión, M., González-Álvaro, I., Rodríguez-Frade, J. M., Mellado, M., Martínez, C., Gomariz, R. P., Juarranz, Y. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6517580/ https://www.ncbi.nlm.nih.gov/pubmed/31089161 http://dx.doi.org/10.1038/s41598-019-43717-2 |
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