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The HuR CMLD-2 inhibitor exhibits antitumor effects via MAD2 downregulation in thyroid cancer cells

Hu antigen R (HuR) is indeed one of the most studied RNA-binding protein (RBP) since its fundamental role both in tumorigenesis and cancer progression. For this reason, downregulation in HuR protein levels or inhibition of HuR biological function are, nowadays, attractive goals in cancer research. H...

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Detalles Bibliográficos
Autores principales: Allegri, Lorenzo, Baldan, Federica, Roy, Sudeshna, Aubé, Jeffrey, Russo, Diego, Filetti, Sebastiano, Damante, Giuseppe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6517587/
https://www.ncbi.nlm.nih.gov/pubmed/31089242
http://dx.doi.org/10.1038/s41598-019-43894-0