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The HuR CMLD-2 inhibitor exhibits antitumor effects via MAD2 downregulation in thyroid cancer cells
Hu antigen R (HuR) is indeed one of the most studied RNA-binding protein (RBP) since its fundamental role both in tumorigenesis and cancer progression. For this reason, downregulation in HuR protein levels or inhibition of HuR biological function are, nowadays, attractive goals in cancer research. H...
Autores principales: | Allegri, Lorenzo, Baldan, Federica, Roy, Sudeshna, Aubé, Jeffrey, Russo, Diego, Filetti, Sebastiano, Damante, Giuseppe |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6517587/ https://www.ncbi.nlm.nih.gov/pubmed/31089242 http://dx.doi.org/10.1038/s41598-019-43894-0 |
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