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Silencing LGR6 Attenuates Stemness and Chemoresistance via Inhibiting Wnt/β-Catenin Signaling in Ovarian Cancer

Leucine-rich-repeat-containing G protein-coupled receptors (LGRs) have been widely found to be implicated with development and progression in multiple cancer types. However, the clinical significance and biological functions of LGR6 in ovarian cancer remains unclear. In this study, LGR6 expression w...

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Detalles Bibliográficos
Autores principales: Ruan, Xiaohong, Liu, Aibin, Zhong, Meigong, Wei, Jihong, Zhang, Weijian, Rong, Yingrou, Liu, Wanmin, Li, Mingwei, Qing, Xingrong, Chen, Gaowen, Li, Ronggang, Liao, Yuehua, Liu, Qiongru, Zhang, Xin, Ren, Dong, Wang, Yifeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6517611/
https://www.ncbi.nlm.nih.gov/pubmed/31193124
http://dx.doi.org/10.1016/j.omto.2019.04.002