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The yeast mitochondrial pyruvate carrier is a hetero‐dimer in its functional state

The mitochondrial pyruvate carrier (MPC) is critical for cellular homeostasis, as it is required in central metabolism for transporting pyruvate from the cytosol into the mitochondrial matrix. MPC has been implicated in many diseases and is being investigated as a drug target. A few years ago, small...

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Detalles Bibliográficos
Autores principales: Tavoulari, Sotiria, Thangaratnarajah, Chancievan, Mavridou, Vasiliki, Harbour, Michael E, Martinou, Jean‐Claude, Kunji, Edmund RS
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6517818/
https://www.ncbi.nlm.nih.gov/pubmed/30979775
http://dx.doi.org/10.15252/embj.2018100785