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The yeast mitochondrial pyruvate carrier is a hetero‐dimer in its functional state
The mitochondrial pyruvate carrier (MPC) is critical for cellular homeostasis, as it is required in central metabolism for transporting pyruvate from the cytosol into the mitochondrial matrix. MPC has been implicated in many diseases and is being investigated as a drug target. A few years ago, small...
Autores principales: | Tavoulari, Sotiria, Thangaratnarajah, Chancievan, Mavridou, Vasiliki, Harbour, Michael E, Martinou, Jean‐Claude, Kunji, Edmund RS |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6517818/ https://www.ncbi.nlm.nih.gov/pubmed/30979775 http://dx.doi.org/10.15252/embj.2018100785 |
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