NCL1, A Highly Selective Lysine-Specific Demethylase 1 Inhibitor, Suppresses Castration-Resistant Prostate Cancer Growth via Regulation of Apoptosis and Autophagy

Recent studies have shown that epigenetic alterations lead to oncogenic activation, thus indicating that these are therapeutic targets. Herein, we analyzed the efficacy and therapeutic potential of our developed histone lysine demethylase 1 (LSD1) inhibitor, NCL1, in castration-resistant prostate ca...

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Detalles Bibliográficos
Autores principales: Etani, Toshiki, Naiki, Taku, Naiki-Ito, Aya, Suzuki, Takayoshi, Iida, Keitaro, Nozaki, Satoshi, Kato, Hiroyuki, Nagayasu, Yuko, Suzuki, Shugo, Kawai, Noriyasu, Yasui, Takahiro, Takahashi, Satoru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6517972/
https://www.ncbi.nlm.nih.gov/pubmed/30935141
http://dx.doi.org/10.3390/jcm8040442

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6517972/
https://www.ncbi.nlm.nih.gov/pubmed/30935141
http://dx.doi.org/10.3390/jcm8040442

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