PARP Inhibitors as a Therapeutic Agent for Homologous Recombination Deficiency in Breast Cancers

Poly (ADP-ribose) polymerases (PARPs) play an important role in various cellular processes, such as replication, recombination, chromatin remodeling, and DNA repair. Emphasizing PARP’s role in facilitating DNA repair, the PARP pathway has been a target for cancer researchers in developing compounds...

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Detalles Bibliográficos
Autores principales: Keung, Man Yee T., Wu, Yanyuan, Vadgama, Jaydutt V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6517993/
https://www.ncbi.nlm.nih.gov/pubmed/30934991
http://dx.doi.org/10.3390/jcm8040435

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6517993/
https://www.ncbi.nlm.nih.gov/pubmed/30934991
http://dx.doi.org/10.3390/jcm8040435

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