The Effect of Wnt Pathway Modulators on Human iPSC-Derived Pancreatic Beta Cell Maturation

Current published protocols for targeted differentiation of human stem cells toward pancreatic β-cells fail to deliver sufficiently mature cells with functional properties comparable to human islet β-cells. We aimed to assess whether Wnt-modulation could promote the final protocol stages of β-cell m...

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Detalles Bibliográficos
Autores principales: Vethe, Heidrun, Ghila, Luiza, Berle, Magnus, Hoareau, Laurence, Haaland, Øystein A., Scholz, Hanne, Paulo, Joao A., Chera, Simona, Ræder, Helge
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Endocrinology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6518024/
https://www.ncbi.nlm.nih.gov/pubmed/31139151
http://dx.doi.org/10.3389/fendo.2019.00293

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6518024/
https://www.ncbi.nlm.nih.gov/pubmed/31139151
http://dx.doi.org/10.3389/fendo.2019.00293

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