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A beta cell ATGL-lipolysis/adipose tissue axis controls energy homeostasis and body weight via insulin secretion in mice

AIMS/HYPOTHESIS: To directly assess the role of beta cell lipolysis in insulin secretion and whole-body energy homeostasis, inducible beta cell-specific adipose triglyceride lipase (ATGL)-deficient (B-Atgl-KO) mice were studied under normal diet (ND) and high-fat diet (HFD) conditions. METHODS: Atgl...

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Detalles Bibliográficos
Autores principales: Attané, Camille, Peyot, Marie-Line, Lussier, Roxane, Poursharifi, Pegah, Zhao, Shangang, Zhang, Dongwei, Morin, Johane, Pineda, Marco, Wang, Shupei, Dumortier, Olivier, Ruderman, Neil B., Mitchell, Grant A., Simons, Brigitte, Madiraju, S. R. Murthy, Joly, Erik, Prentki, Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6518076/
https://www.ncbi.nlm.nih.gov/pubmed/27677764
http://dx.doi.org/10.1007/s00125-016-4105-2